The Canary Database
Yale Occupational and
Environmental Medicine Program
135 College St
Room 366
New Haven, CT, USA
06510-2283
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Toxicol Sci 2000 Oct;57(2):264-74.
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Stage- and species-specific developmental toxicity of all-trans retinoic acid in four native North American ranids and Xenopus laevis.
Degitz SJ, Kosian PA, Makynen EA, Jensen KM, Ankley GT
U.S. Environmental Protection Agency, Mid-Continent Ecology Division, 6201 Congdon Boulevard, Duluth, Minnesota 55804, USA. degitz.sigmund@epamail.epa.gov
Article type: Curated - Canary ID: 1654
| Cause and Effect Analysis |
Interspecies susceptibility data |
Shared exposures with humans |
Shared outcomes with humans |
Gene sequence data |
| Yes |
Yes |
No |
No |
No |
| Study type |
N |
Routes |
Sampling |
Controls |
Timing |
| experimental |
210 |
ingestion, other |
- |
- |
- |
| Exposures |
Vitamin A
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| Risk factors |
Species Specificity
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| Outcomes |
Abnormalities, Multiple
Anophthalmos
Holoprosencephaly
Lethal Dose 50
Limb Deformities, Congenital
Mortality
Survival
toxicity <1>
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| Species |
Rana clamitans
Rana pipiens
Rana septentrionalis
Wood frog
Xenopus laevis
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